Wiley MB, Bauer J, Alvarez V, Kolics Z, Cheng W, Church DN, Kerr DJ, Kerr RS, Jung B. Activin A Affects Colorectal Cancer in a Stage Dependent Manner. Sci Rep. March 12, 2025. PMID: 40075112; PMCID: PMC11903883
Wiley MB, Bauer J, Alvarez V, Mehrotra K, Cheng W, Kolics Z, Giarrizzo M, Ingle K, Bialkowska A, Jung B. Activin A Signaling Stimulates Neutrophil Activation and Macrophage Migration in Pancreatitis. Sci Rep. April 23, 2024. PMID: 38654064; PMCID: PMC11039671
Wiley MB, Mehrotra K, Bauer J, Yazici C, Bialkowska A, Jung B. Acute Pancreatitis: Current Clinical Approaches, Molecular Pathophysiology, and Potential Therapeutics. Pancreas. July 1, 2023. PMID: 38127317; PMCID: PMC11913250
Wiley MB, Bauer J, Mehrotra KM, Zessner-Spitzenberg J, Kone, L, Quiao G, Castellanos K, Church DN, Kerr RS, Kerr DJ, Grippo P, Maker A, Jung B. Non-Canonical Activin A Signaling Stimulates Context-Dependent and Cellular-Specific Outcomes in CRC to Promote Tumor Cell Migration and Immune Tolerance. Cancers. May 31, 2023. PMID: 37296966; PMCID: PMC10252122
Staudacher JJ, Bauer J, Atkinson SR, Thursz M, Lang S, Schnabl B, Wiley MB, Carr R, Jung B. Systemic Activin Is Elevated in Patients With Severe Alcoholic Hepatitis. Gastro Hep Adv. 2022;1(2):147-149. Epub 2022 Feb 7. PMID: 35602917; PMCID: PMC9119346.
Mancinelli G, Torres C, Krett N, Bauer J, Castellanos K, McKinney R, Dawson D, Guzman G, Hwang R, Grimaldo S, Grippo P, Jung B. Role of Stromal Activin A in Human Pancreatic Cancer and Metastasis in Mice. Sci Rep. 2021 Apr 12;11(1):7986. PMID: 33846512; PMCID: PMC8042028.
Thomas AL, Castellanos K, Mancinelli G, Xia Y, Bauer J, Yazici C, Fantuzzi G, Hwang RF, Krett NL, Papachristou GI, Whitcomb DC, Jung B. Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index. Clin Transl Gastroenterol. 2020 May;11(5):e00152. PMID: 32358238; PMCID: PMC7263641.
Jana A, Das A, Krett NL, Guzman G, Thomas A, Mancinelli G, Bauer J, Ushio-Fukai M, Fukai T, Jung B. Nuclear Translocation of Atox1 Potentiates Activin A-Induced Cell Migration and Colony Formation in Colon Cancer. PLoS One. 2020;15(1):e0227916. eCollection 2020. PMID: 31961892; PMCID: PMC6974162.
Bauer J, Emon MAB, Staudacher JJ, Thomas AL, Zessner-Spitzenberg J, Mancinelli G, Krett N, Saif MT, Jung B. Increased Stiffness of the Tumor Microenvironment in Colon Cancer Stimulates Cancer Associated Fibroblast-Mediated Prometastatic Activin A Signaling. Sci Rep. 2020 Jan 9;10(1):50. PMID: 31919369; PMCID: PMC6952350.
Zessner-Spitzenberg J, Thomas AL, Krett NL, Jung B. TGFβ and Activin A in the Tumor Microenvironment in Colorectal Cancer. Gene Rep. 2019 Dec;17. Epub 2019 Sep 12. PMID: 32154442; PMCID: PMC7061929.
Yazici C, Geary K, Sanchez A, Boulay BR, Papachristou GI, Krett N, Grippo PJ, Jung B. African Americans With Acute Pancreatitis Present With Worsened Kidney Injury and Have Inadequate Access to Care. Pancreas. 2019 Oct;48(9):e66-e68. PMID: 31609935; PMCID: PMC6801107.
Emon B, Bauer J, Jain Y, Jung B, Saif T. Biophysics of Tumor Microenvironment and Cancer Metastasis – A Mini Review. Comput Struct Biotechnol J. 2018;16:279-287. eCollection 2018. Review. PMID: 30128085; PMCID: PMC6097544.
Sahni S, Shiralkar M, Mohamed S, Carroll R, Jung B, Gaba R, Yazici C. Superior Mesenteric Artery Syndrome: The Dark Side of Weight Loss. Cureus. 2017 Nov 18;9(11):e1859. PMID: 29375945; PMCID: PMC5773266.
Yazici C, Wolf PG, Kim H, Cross TL, Vermillion K, Carroll T, Augustus GJ, Mutlu E, Tussing-Humphreys L, Braunschweig C, Xicola RM, Jung B, Llor X, Ellis NA, Gaskins HR. Race-Dependent Association of Sulfidogenic Bacteria with Colorectal Cancer. Gut. 2017 Nov;66(11):1983-1994. Epub 2017 Feb 2. PMID: 28153960; PMCID: PMC5575988.
Staudacher JJ, Yazici C, Bul V, Zeidan J, Khalid A, Xia Y, Krett N, Jung B. Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer. Clin Transl Gastroenterol. 2017 Oct 19;8(10):e124. PMID: 29048416; PMCID: PMC5666119.
Staudacher JJ, Yazici C, Carroll T, Bauer J, Pang J, Krett N, Xia Y, Wilson A, Papachristou G, Dirmeier A, Kunst C, Whitcomb DC, Fantuzzi G, Jung B. Activin in Acute Pancreatitis: Potential Risk-Stratifying Marker and Novel Therapeutic Target. Sci Rep. 2017 Oct 6;7(1):12786. PMID: 28986573; PMCID: PMC5630611.
Staudacher JJ, Bauer J, Jana A, Tian J, Carroll T, Mancinelli G, Özden Ö, Krett N, Guzman G, Kerr D, Grippo P, Jung B. Activin Signaling is an Essential Component of the TGF-β Induced Pro-Metastatic Phenotype in Colorectal Cancer. Sci Rep. 2017 Jul 17;7(1):5569. PMID: 28717230; PMCID: PMC5514149.
Bul V, Yazici C, Staudacher JJ, Jung B, Boulay BR. Multiorgan Failure Predicts Mortality in Emphysematous Pancreatitis: A Case Report and Systematic Analysis of the Literature. Pancreas. 2017 Jul;46(6):825-830. Review. PMID: 28609373; PMCID: PMC5470594.
Jana A, Krett NL, Guzman G, Khalid A, Ozden O, Staudacher JJ, Bauer J, Baik SH, Carroll T, Yazici C, Jung B. NFkB is Essential for Activin-Induced Colorectal Cancer Migration via Upregulation of PI3K-MDM2 Pathway. Oncotarget. 2017 Jun 6;8(23):37377-37393. PMID: 28418896; PMCID: PMC5514916.
Principe DR, DeCant B, Staudacher J, Vitello D, Mangan RJ, Wayne EA, Mascariñas E, Diaz AM, Bauer J, McKinney RD, Khazaie K, Pasche B, Dawson DW, Munshi HG, Grippo PJ, Jung B. Loss of TGFβ Signaling Promotes Colon Cancer Progression and Tumor-Associated Inflammation. Oncotarget. 2017 Jan 17;8(3):3826-3839. PMID: 27270652; PMCID: PMC5354798.
Jung B, Staudacher JJ, Beauchamp D. Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer. Gastroenterology. 2017 Jan;152(1):36-52. Epub 2016 Oct 20. Review. PMID: 27773809; PMCID: PMC5550896.
Ozden O, Bishehsari F, Bauer J, Park SH, Jana A, Baik SH, Sporn JC, Staudacher JJ, Yazici C, Krett N, Jung B. Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer. Sci Rep. 2016 May 20;6:26273. PMID: 27197561; PMCID: PMC4873788.
Principe DR, DeCant B, Diaz AM, Mangan RJ, Hwang R, Lowy A, Shetuni BB, Sreekumar BK, Chung C, Bentrem DJ, Munshi HG, Jung B, Grippo PJ, Bishehsari F. PEDF Inhibits Pancreatic Tumorigenesis by Attenuating the Fibro-Inflammatory Reaction. Oncotarget. 2016 May 10;7(19):28218-34. PMID: 27058416; PMCID: PMC5053722.
Principe DR, DeCant B, Mascariñas E, Wayne EA, Diaz AM, Akagi N, Hwang R, Pasche B, Dawson DW, Fang D, Bentrem DJ, Munshi HG, Jung B, Grippo PJ. TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis. Cancer Res. 2016 May 1;76(9):2525-39. Epub 2016 Mar 15. PMID: 26980767; PMCID: PMC4873388.
Bauer J, Staudacher JJ, Krett NL, Jung B. Commentary: Activin and TGFβ Use Diverging Mitogenic Signaling in Advanced Colon Cancer. J Rare Dis Res Treat. 2016;1(1):43-45. PMID: 27738666; PMCID: PMC5058340.
Bauer J, Ozden O, Akagi N, Carroll T, Principe DR, Staudacher JJ, Spehlmann ME, Eckmann L, Grippo PJ, Jung B. Activin and TGFβ use Diverging Mitogenic Signaling in Advanced Colon Cancer. Mol Cancer. 2015 Oct 24;14:182. PMID: 26497569; PMCID: PMC4619565.
Bishehsari F, Gach JS, Akagi N, Webber MK, Bauer J, Jung BH. Anti-p21 Autoantibodies Detected in Colorectal Cancer Patients: A Proof of Concept Study. Oncoimmunology. 2014;3(8):e952202. eCollection 2014. PMID: 25960931; PMCID: PMC4368126.
Ozden O, Park SH, Wagner BA, Song HY, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D. SIRT3 Deacetylates and Increases Pyruvate Dehydrogenase Activity in Cancer Cells. Free Radic Biol Med. 2014 Nov;76:163-172. Epub 2014 Aug 22. PMID: 25152236; PMCID: PMC4364304.
Jung B. GRG update: DDW 2014. Dig Dis Sci. 2014 Jul;59(7):1341-3. Epub 2014 Jun 13. PMID: 24925150.
Principe DR, Doll JA, Bauer J, Jung B, Munshi HG, Bartholin L, Pasche B, Lee C, Grippo PJ. TGF-β: Duality of Function Between Tumor Prevention and Carcinogenesis. J Natl Cancer Inst. 2014 Feb;106(2):djt369. Review. PMID: 24511106; PMCID: PMC3952197.
Gach JS, Achenbach CJ, Chromikova V, Berzins B, Lambert N, Landucci G, Forthal DN, Katlama C, Jung BH, Murphy RL. HIV-1 Specific Antibody Titers and Neutralization Among Chronically Infected Patients on Long-Term Suppressive Antiretroviral Therapy (ART): A Cross-Sectional Study. PLoS One. 2014;9(1):e85371. eCollection 2014. PMID: 24454852; PMCID: PMC3893210.
Gawron AJ, Jung B, Fought AJ, Waldman BH, Parikh ND. A Colorectal Cancer Screening Program in an Underserved, Ethnically Diverse Population in Chicago, IL. J Community Health. 2013 Aug;38(4):603-8. PMID: 23471656; PMCID: PMC3706552.
Secemsky BJ, Robinson KR, Krishnan K, Matkowskyj KA, Jung BH. Gastric Hyperplastic Polyps Causing Upper Gastrointestinal Hemorrhage in a Young Adult. World J Clin Cases. 2013 Apr 16;1(1):25-7. PMID: 24303456; PMCID: PMC3845928.
Jiménez JA, Jung B, Madlensky L. Physician-Patient and Patient-Family Communication After Colonoscopy. Am J Gastroenterol. 2012 Sep;107(9):1288-95. PMID: 22951870.
Bauer J, Sporn JC, Cabral J, Gomez J, Jung B. Effects of Activin and TGFβ on p21 in Colon Cancer. PLoS One. 2012;7(6):e39381. Epub 2012 Jun 26. PMID: 22761777; PMCID: PMC3383701.
Sporn JC, Jung B. Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer. Am J Pathol. 2012 Jun;180(6):2516-26. Epub 2012 Apr 27. PMID: 22542848; PMCID: PMC3717782.
Laghi L, Bianchi P, Delconte G, Celesti G, Di Caro G, Pedroni M, Chiaravalli AM, Jung B, Capella C, de Leon MP, Malesci A. MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers. Clin Cancer Res. 2012 Jun 1;18(11):3142-53. Epub 2012 Apr 10. PMID: 22496206.
Lee SY, Miyai K, Han HS, Hwang DY, Seong MK, Chung H, Jung BH, Devaraj B, McGuire KL, Carethers JM. Microsatellite Instability, EMAST, and Morphology Associations with T Cell Infiltration in Colorectal Neoplasia. Dig Dis Sci. 2012 Jan;57(1):72-8. Epub 2011 Jul 20. PMID: 21773681; PMCID: PMC3245369.
Sporn JC, Hothorn T, Jung B. BARD1 Expression Predicts Outcome in Colon Cancer. Clin Cancer Res. 2011 Aug 15;17(16):5451-62. Epub 2011 Jun 21. PMID: 21693656; PMCID: PMC3372413.
Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P. Expression of GIV/Girdin, a Metastasis-Related Protein, Predicts Patient Survival in Colon Cancer. FASEB J. 2011 Feb;25(2):590-9. Epub 2010 Oct 25. PMID: 20974669; PMCID: PMC3023389.
Lee SY, Chung H, Devaraj B, Iwaizumi M, Han HS, Hwang DY, Seong MK, Jung BH, Carethers JM. Microsatellite Alterations at Selected Tetranucleotide Repeats are Associated with Morphologies of Colorectal Neoplasias. Gastroenterology. 2010 Nov;139(5):1519-25. Epub 2010 Aug 11. PMID: 20708618; PMCID: PMC2967646.
Jung B, Gomez J, Chau E, Cabral J, Lee JK, Anselm A, Slowik P, Ream-Robinson D, Messer K, Sporn J, Shin SK, Boland CR, Goel A, Carethers JM. Activin Signaling in Microsatellite Stable Colon Cancers is Disrupted by a Combination of Genetic and Epigenetic Mechanisms. PLoS One. 2009 Dec 14;4(12):e8308.PMID: 20011542; PMCID: PMC2789408.
Link A, Shin SK, Nagasaka T, Balaguer F, Koi M, Jung B, Boland CR, Goel A. JC Virus Mediates Invasion and Migration in Colorectal Metastasis. PLoS One. 2009 Dec 3;4(12):e8146. doi: 10.1371/journal.pone.0008146. PubMed PMID: 19997600; PubMed Central PMCID: PMC2781631.
Scharl M, Paul G, Weber A, Jung BC, Docherty MJ, Hausmann M, Rogler G, Barrett KE, McCole DF. Protection of Epithelial Barrier Function by the Crohn’s Disease Associated Gene Protein Tyrosine phosphatase n2. Gastroenterology. 2009 Dec;137(6):2030-2040.e5. doi: 10.1053/j.gastro.2009.07.078. Epub 2009 Oct 8. PubMed PMID: 19818778; PubMed Central PMCID: PMC2855721.
Zhang YQ, Resta S, Jung B, Barrett KE, Sarvetnick N. Upregulation of Activin Signaling in Experimental Colitis. Am J Physiol Gastrointest Liver Physiol. 2009 Oct;297(4):G768-80. doi: 10.1152/ajpgi.90631.2008. Epub 2009 Jul 30. PubMed PMID: 19643954; PubMed Central PMCID: PMC2763799.
Jung BH, Beck SE, Carethers JM. Bone Morphogenetic Protein (BMP) and Activin Signaling in Experimental Colitis. Current Cancer Reports. 2008; 4:71076.
Shin SK, Nagasaka T, Jung BH, Matsubara N, Kim WH, Carethers JM, Boland CR, Goel A. Epigenetic and Genetic Alterations in Netrin-1 Receptors UNC5C and DCC in Human Colon Cancer. Gastroenterology. 2007 Dec;133(6):1849-57. doi: 10.1053/j.gastro.2007.08.074. Epub 2007 Sep 5. PubMed PMID: 18054557; PubMed Central PMCID: PMC4139066.
Beck SE, Jung BH, Del Rosario E, Gomez J, Carethers JM. BMP-Induced Growth Suppression in Colon Cancer Cells is Mediated by p21WAF1 Stabilization and Modulated by RAS/ERK. Cell Signal. 2007 Jul;19(7):1465-72. doi: 10.1016/j.cellsig.2007.01.017. Epub 2007 Jan 24. PubMed PMID: 17317101; PubMed Central PMCID: PMC3444522.
Owens DJ, Jung B. Duodenal Thrombotic Thrombocytopenic Purpura. Clin Gastroenterol Hepatol. 2007 Apr;5(4):e15. Epub 2007 Mar 12. PMID: 17350895.
Jung BH, Beck SE, Cabral J, Chau E, Cabrera BL, Fiorino A, Smith EJ, Bocanegra M, Carethers JM. Activin Type 2 Receptor Restoration in MSI-H Colon Cancer Suppresses Growth and Enhances Migration with Activin. Gastroenterology. 2007 Feb;132(2):633-44.. Epub 2006 Nov 16. PMID: 17258738; PMCID: PMC4154562.
Gosh P, Jung B. Giant Paraesophageal Hernia Causing Compression Pulmonary Atelectasis: Starved for Air When Satiated with Food. J Gastroenterol and Hepatology. 2007; 22(4):595.
Beck SE, Jung BH, Fiorino A, Gomez J, Rosario ED, Cabrera BL, Huang SC, Chow JY, Carethers JM. Bone Morphogenetic Protein Signaling and Growth Suppression in Colon Cancer. Am J Physiol Gastrointest Liver Physiol. 2006 Jul;291(1):G135-45. PMID: 16769811; PMCID: PMC4138725.
Jung B, Smith EJ, Doctolero RT, Gervaz P, Alonso JC, Miyai K, Keku T, Sandler RS, Carethers JM. Influence of Target Gene Mutations on Survival, Stage and Histology in Sporadic Microsatellite Unstable Colon Cancers. Int J Cancer. 2006 May 15;118(10):2509-13. PMID: 16380996; PMCID: PMC4155491.
Jung B, Barbier V, Brickner H, Welsh J, Fotedar A, McClelland M. Mechanisms of Sulindac-Induced Apoptosis and Cell Cycle Arrest. Cancer Lett. 2005 Feb 28;219(1):15-25. PMID: 15694660.
Jung B, Steinbach J, Beaumont C, Mittal RK. Lack of Association Between Esophageal Acid Sensitivity Detected by Prolonged pH Monitoring and Bernstein Testing. Am J Gastroenterol. 2004 Mar;99(3):410-5. PMID: 15056077.
Jung B, Doctolero RT, Tajima A, Nguyen AK, Keku T, Sandler RS, Carethers JM. Loss of Activin Receptor Type 2 Protein Expression in Microsatellite Unstable Colon Cancers. Gastroenterology. 2004 Mar;126(3):654-9. PMID: 14988818; NIHMSID:NIHMS209569.
Jung B, Carethers JM, Behling C, Garvie JJ. Aphthous Colitis in a Young Man with Diverticulitis. Gastrointest Endosc. 2003 Aug;58(2):301-4. PMID: 12872111.
Lechner S, Müller-Ladner U, Schlottmann K, Jung B, McClelland M, Rüschoff J, Welsh J, Schölmerich J, Kullmann F. Bile Acids Mimic Oxidative Stress Induced Upregulation of Thioredoxin Reductase in Colon Cancer Cell Lines. Carcinogenesis. 2002 Aug;23(8):1281-8. PMID: 12151345.
Vogt T, McClelland M, Jung B, Popova S, Bogenrieder T, Becker B, Rumpler G, Landthaler M, Stolz W. Progression and NSAID-Induced Apoptosis in Malignant Melanomas are Independent of Cyclooxygenase II. Melanoma Res. 2001 Dec;11(6):587-99. PMID: 11725205.
Chantalat L, Skoufias DA, Kleman JP, Jung B, Dideberg O, Margolis RL. Crystal Structure of Human Survivin Reveals a Bow Tie-Shaped Dimer with Two Unusual Alpha-Helical Extensions. Mol Cell. 2000 Jul;6(1):183-9. PMID: 10949039.
Fotedar R, Brickner H, Saadatmandi N, Rousselle T, Diederich L, Munshi A, Jung B, Reed JC, Fotedar A. Effect of p21waf1/cip1 Transgene on Radiation Induced Apoptosis in T Cells. Oncogene. 1999 Jun 17;18(24):3652-8. PMID: 10380888.
Jung B, Vogt T, Mathieu-Daudé F, Welsh J, McClelland M, Trenkle T, Weitzel C, Kullmann F. Estrogen-Responsive RING Finger mRNA Induction in Gastrointestinal Carcinoma Cells Following Bile Acid Treatment. Carcinogenesis. 1998 Nov;19(11):1901-6. PubMed PMID: 9855000.
Vogt T, Stolz W, Welsh J, Jung B, Kerbel RS, Kobayashi H, Landthaler M, McClelland M. Overexpression of Lerk-5/Eplg5 Messenger RNA: a Novel Marker for Increased Tumorigenicity and Metastatic Potential in Human Malignant Melanomas. Clin Cancer Res. 1998 Mar;4(3):791-7. PMID: 9533549.
Vogt TM, Welsh J, Stolz W, Kullmann F, Jung B, Landthaler M, McClelland M. RNA Fingerprinting Displays UVB-Specific Disruption of Transcriptional Control in Human Melanocytes. Cancer Res. 1997 Aug 15;57(16):3554-61. PMID: 9270028.
