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Division of Gastroenterology & Hepatology Gastroenterology & Hepatology

Patient-Oriented Research

Our research group is conducting a broad spectrum of clinical trials.

Ongoing Clinical Studies

SAMARA

Status: Currently recruiting subjects

Study Description: The primary goal of this study is to demonstrate that subcutaneous administration of semaglutide 2.4 mg weekly for 52 weeks improves non-invasive measures of fibrosis in high-risk patients who have significant fibrosis due to MASLD.

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San Diego Liver Study (SDL)

Status: Currently recruiting subjects

Study Description: The purpose of this study is to estimate the accurate prevalence of accumulation of fat in the liver (steatosis) and scar tissue formation (fibrosis) in overweight or obese adult participants from the Greater San Diego Area.

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Type 2 Diabetes Observational Study (DOS)

Status: Currently recruiting subjects

Study Description: The aim of the study is to estimate the accurate prevalence of MASLD and advanced fibrosis in a cohort of T2DM patients older than 50 years of age.

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GOLDMINE Study

Status: Currently recruiting subjects

Study Description: The aim of the study is to understand which baseline prognostic factors are associated with the progression of MASLD and to evaluate the progression of MASLD using non-invasive imaging techniques.

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The MASLD Registry Study

Status: Currently recruiting subjects

Study Description: The purpose of the MASLD Registry study is to better understand MASLD by following and evaluating people, yearly, with or without this condition.

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The Adult Database 3 Study

Status: Currently recruiting subjects

Study Description: The primary objective of the study is to investigate the etiology, pathogenesis, natural history, diagnosis, treatment, and prevention of MASLD and MASH.

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The Twin and Family Study

Status: Currently recruiting subjects

Study Description: This study aims to investigate the heritability of fatty liver in twin pairs and first-degree relatives.

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LCN (Liver Cirrhosis Network)

Status: Currently recruiting subjects

Study Description:  The main goals of the study are to uncover the underlying reasons and mechanisms behind the onset of complications in patients with cirrhosis and initiate a trial to investigate whether the administration of a statin can enhance the overall health outcomes of individuals afflicted with cirrhosis.

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Familial Cirrhosis

Status: Currently recruiting subjects

Required visits: Single visit

Age of participants: Greater than 18 years

Gender of participants: Male and Female

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San Diego Cirrhosis Registry Study

Status: Currently recruiting subjects

Required visits: Single visit

Age of participants: Greater than 18 years

Gender of participants: Male and Female

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Heavy Water Study

Status: Currently recruiting subjects

Required visits: Four visits

Age of participants: Greater than 18 years

Gender of participants: Male and Female

Alpha-1 Antitrypsin Deficiency Study

Status: Currently recruiting subjects

Required visits: Single visit

Age of participants: Greater than 18 years

Gender of participants: Male and Female